ea0022p354 | Diabetes | ECE2010
Elowe-Gruau Eglantine
, Dal-Ros Stephanie
, Auberval Nathalie
, Seyfritz Elodie
, Bietiger William
, Pinget Michel
, Jeandidier Nathalie
, Sigrist Severine
Hyperaldosteronism and diabetes are two providers of kidney disease, showing molecular and cellular mechanisms in common, such as oxidative stress, causing renal tubular damages. The objective of this study is to evaluate in vitro the protective effect of a natural antioxidant (red wine polyphenols and green tea extract) in the onset of renal dysfunction. Hyperglycemia and hyperaldosteronism are induced respectively by increasing doses of glucose and aldosterone in prim...